Novel technique in the management of intraoral alkali-induced chemical burn

Title: Novel technique in the management of intraoral alkali-induced chemical burn

Abstract:

The composition of the oral mucosa and skin may bearing little resemblance, however the responses of the oral mucosa to burn injuries resulting in different histopathological and clinical consequences. The unique biology and localization of the oral mucosa requires an altogether separate treatment methodology in burn injuries. In our report we would like to present a case of a 11-year old male patient who was involved in accidentally swallowing alkaline solution, which left him with severe scarring in the oral cavity. His main complaint was limited mouth opening, difficulties in speech.
Materials and Methods: The complex treatment method was conducted during the timeperiod between June 2022- November 2023. The first therapeutic step included local administration of corticosteroids at intervals of three months. After carefully administered local anaesthesia ( 2ml of Septanest (articain-hidroclorid), 2ml of Kenalog ™ (triamcinolon- acetonid) per each buccal side was injected intraorally in the affected region in three session. As a final step autologous fat transfer was performed under general anaesthesia. The autologous fat was grafted from the abdomen region with a Seffiller kit for guided tissue harvesting. A total amount of 6ml fat and stromal fractional stem cells were injected.
Results: After analyzing the results of the corticosteroid-induced healing process, we concluded, that the results were not promising. The injections could not significantly eliminate the scar-formation, which left the patient with a compromised mouth opening. The applied regenerative therapeutic method, the Seffiller kit, was able to reduce contracture rates on palpation and as well the maximum of the mouth opening could be increased.
Conclusions: Although there are guidelines for regarding for the management of the chemical burns for the skin, there is no standardised algorythm for the intraoral burn scars. In our patient, a complex therapeutic modality was composed.

Biography:

Dr. Jancsik studied Dentistry at the University Of Pecs, Hungary and graduated as DMD in 2012. She then joined the research group of Prof. Olasz at the Department Of Oral and Maxillofacial Surgery, University of Pecs, Hungary, and the Doctoral Programme. She received her PhD degree in 2015 at the same institution. In 2016 supervised by Professor Piffko she received a Master of Science Implantology & Dental Surgery. In 2018 she graduated in Oral Surgery, Postgraduate training at the University of Szeged, Hungary. She won numerous prestigious awards both nationally as well as internationally, her cumulative impact factor score is: 16.681.