Title: Evaluation of the FSH, LH and prolactin serum level in patients with Oral Lichen Planus in comparison to healthy population
Aim and Background: In this study we aimed to evaluate any possible relation of FSH, LH and prolactin level and oral lichen planus (OLP).
Materials and methods: In this cross sectional study, the serum level of LH, FSH, Prolactin of 40 women with lichen planus who have been referred to Shiraz Dental Faculty, Oral and Maxillofacial Disease Department during 2018-2019 have been evaluated in comparison to 40 healthy controls. Data were analyzed by SPSS version 18. Two Way ANOVA and Mann Whitney test was used for data analysis.
Results: The mean serum level of FSH and LH were significantly higher in OLP patients while this difference was not reported for prolactin. Only FSH mean serum level was significantly higher in non-menopausal OLP patients. The distribution of prolactin and FSH hormones’ serum level was in normal range.
Conclusions: The high serum level of FSH and LH can affect OLP pathogenesis by estrogen and progesterone modulation.