Title: Development, clinical and microbiological study of low abrasivity dentifrice for the control of candida albicans in dental prostheses
The dental prosthesis has the function of restoring function and aesthetics to the edentulous patient. However, its use requires a lot of important care, since oral rehabilitation does not only mean the installation of the prosthesis in the patient's mouth, but the treatment and the hygiene of the same and the tissues of the oral cavity as well. Oral hygiene and prosthetic devices promote greater longevity of the prosthetic treatment performed, since the accumulation of bacterial biofilm and fungal infections on the resin that forms the prosthesis saddle can lead, as a consequence, to inflammatory papillary hyperplasia, prosthetic stomatitis and chronic candidiasis. The dentifrices present in their formulations abrasive components - poorly soluble inorganic salts, which aim to remove stains and assist in the removal of the biofilm. Among the abrasives, soluble sodium bicarbonate causes less wear than insoluble calcium carbonate, which is highly abrasive. Abrasion of the acrylic surface is a negative factor of the common dentifrices, which results in the excessive wear and deterioration of the acrylic with the appearance of grooves that allow the aggregation of residues and microorganisms. Faced with the limitations of mechanical hygiene methods, the action of substances extracted from plants, such as tannins (polyphenols) and phenolic compounds, have been studied as proposed antimicrobial agents because they present specific action in the control or development of microorganisms in dental prostheses and oral mucosa . Punica granatum Linn., Popularly known as pomegranate, a native shrub of Asia, cultivated in warm climate areas have extensively described pharmacological properties, resulting in its indication for various uses, including: immunomodulation, arteriosclerosis, bacterial infection, fungal infection, infection parasite and periodontal disease. This presentation aimed to develop and characterize a low abrasive dentifrice based on hydroalcoholic extracts of Punica granatum Linn (pomegranate) for the microbiological and clinical control of Candida albicans in removable dental prostheses.