Progressive aging of titanium results in a reduction in biological activity, which could be reactivated by ultraviolet (UV) illumination in what is called photofunctionalization.
Objective: to make an update on photofunctionalization in titanium surfaces (disks and cylinders).
Method: systematic review.
Search strategy: a search is made in these electronic databases: TRIPDATABASE, PUBMED / MEDLINE, SCIENCE DIRECT, SCIELO, SCOPUS and COCHRANE PLUS. The articles were selected according to inclusion criteria by All Files, and were subsequently revised to eliminate duplicity.
Selection criteria: include experimental and observational studies analyzing hydrophilicity and osteoconduction by using photofunctionalization in titanium disks or cylinders at different UV wavelengths. The quality of the studies was evaluated following the criteria proposed by Caspe's reading sheets of criticism, and the recommendations proposed by the Scottish Intercollegiate Guidelines Network (SIGN).
Results: 26 studies were included. Photofunctionalization results in a change in the hydrophobic surface of a superhydrophile, transforming a bioenergy surface into bioactive and improving migration, proliferation and cell adhesion, especially on titanium surfaces with micro-nano hybrid topography (nanoscale nodules in microscale pits). A reduction in bacterial accumulation was observed on photofunctionalized titanium surfaces.
Conclusions: photofunctionalization with C-range (λ ≤ 280 nm) UV illumination has shown an improvement in titanium surfaces.